Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278946 | 1.00 | LCK (0.41) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL11278444 | 1.00 | LCK (0.41) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL11278941 | 1.00 | LCK (0.41) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL11278867 | 0.98 | LCK (0.38) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL11278865 | 0.98 | LCK (0.38) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL11278927 | 0.85 | LCK (0.39) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL11288917 | 0.85 | LCK (0.39) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL11288921 | 0.85 | LCK (0.39) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL11278933 | 0.85 | LCK (0.39) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL11276990 | 0.83 | MEN1 (0.40) | LCKPPARDZDHHC20ZDHHC2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000555-B1 | PROCESS FOR THE PREPARATION OF OXIRANES SUBSTITUTED BY HALOGEN ALKYL | BAYER AG (DE) | 1982-02-10 | — | — | EP | disclosed |
| EP-0000554-A1 | Process for the preparation of oxiranes substituted by halogen alkyl | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |
| EP-0000555-A1 | Process for the preparation of oxiranes substituted by halogen alkyl | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |