Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65512 | 0.87 | KDM4E (0.58) | HSD17B10TSHRKDM4EALDH1A1NPC1 | |
| SCHEMBL29385742 | 0.87 | KDM4E (0.58) | HSD17B10TSHRKDM4EALDH1A1NPC1 | |
| SCHEMBL6934866 | 0.87 | KDM4E (0.58) | HSD17B10TSHRKDM4EALDH1A1NPC1 | |
| SCHEMBL29413992 | 0.85 | HSD17B10 (0.61) | HSD17B10TSHRSMN1; SMN2CYP3A4EPHX2 | |
| SCHEMBL31734128 | 0.85 | HSD17B10 (0.61) | HSD17B10TSHRSMN1; SMN2CYP3A4EPHX2 | |
| SCHEMBL4747117 | 0.85 | HSD17B10 (0.61) | HSD17B10TSHRSMN1; SMN2CYP3A4EPHX2 | |
| SCHEMBL11278629 | 0.79 | KDM4E (0.45) | HSD17B10TSHRKDM4EALDH1A1THRB | |
| SCHEMBL132197 | 0.78 | GAA (0.62) | KDM4ENPC1RAB9ACYP3A4EPHX2 | |
| SCHEMBL29772937 | 0.78 | GAA (0.62) | KDM4ENPC1RAB9ACYP3A4EPHX2 | |
| SCHEMBL148873 | 0.74 | HSD17B10 (0.57) | HSD17B10TSHRKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |
| US-4023957-A | Herbicidal 1-thiadiazolyl-5-carbamoyloxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |