Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272095 | 0.88 | TDP1 (0.55) | SCN9ATDP1MEN1KMT2AGAA | |
| SCHEMBL31118331 | 0.82 | SCN9A (0.44) | FBP1SCN9ATDP1ALDH1A1MEN1 | |
| SCHEMBL11272985 | 0.81 | MEN1 (0.53) | ALDH3A1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL28100328 | 0.79 | SCN9A (0.48) | SCN9ATDP1MEN1KMT2ATTR | |
| SCHEMBL29943920 | 0.79 | SCN9A (0.48) | SCN9ATDP1MEN1KMT2ATTR | |
| SCHEMBL10672572 | 0.78 | TDP1 (0.53) | SCN9ATDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL28366683 | 0.77 | SCN9A (0.46) | FBP1SCN9ATDP1MEN1KMT2A | |
| SCHEMBL11367437 | 0.77 | TDP1 (0.57) | SCN9ATDP1MEN1KMT2ATTR | |
| SCHEMBL10666985 | 0.77 | MEN1 (0.45) | FBP1SCN9ATDP1ALDH1A1MEN1 | |
| SCHEMBL10663135 | 0.77 | TDP1 (0.41) | ALDH3A1FBP1SCN9ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063873-A1 | Haloalkoxy-substituted diphenyl ethers; their use as herbicides and in herbicidal compositions and processes of making them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-03 | — | — | EP | disclosed |