Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277038 | 1.00 | TSHR (0.42) | TSHRLMNADNM1THRBADH1B | |
| SCHEMBL17005797 | 1.00 | TSHR (0.42) | TSHRLMNADNM1THRBADH1B | |
| SCHEMBL11281915 | 1.00 | TSHR (0.42) | TSHRLMNADNM1THRBADH1B | |
| SCHEMBL11778733 | 1.00 | TSHR (0.42) | TSHRLMNADNM1THRBADH1B | |
| SCHEMBL11779059 | 1.00 | TSHR (0.42) | TSHRLMNADNM1THRBADH1B | |
| SCHEMBL11774631 | 1.00 | TSHR (0.42) | TSHRLMNADNM1THRBADH1B | |
| SCHEMBL11276000 | 1.00 | TSHR (0.42) | TSHRLMNADNM1THRBADH1B | |
| SCHEMBL11776122 | 1.00 | TSHR (0.42) | TSHRLMNADNM1THRBADH1B | |
| SCHEMBL11775497 | 1.00 | TSHR (0.42) | TSHRLMNADNM1THRBADH1B | |
| SCHEMBL2361753 | 0.98 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000555-B1 | PROCESS FOR THE PREPARATION OF OXIRANES SUBSTITUTED BY HALOGEN ALKYL | BAYER AG (DE) | 1982-02-10 | — | — | EP | disclosed |
| EP-0000554-A1 | Process for the preparation of oxiranes substituted by halogen alkyl | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |
| EP-0000555-A1 | Process for the preparation of oxiranes substituted by halogen alkyl | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |
| US-4036896-A | FREE RADICAL CATALYST | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1977-07-19 | — | — | US | disclosed |