Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR1E | P28566 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11280889 | 0.98 | POLB (0.70) | POLBATMCHRM2CHRM1CHRM3 | |
| SCHEMBL14756184 | 0.85 | CHRM2 (0.63) | POLBATMCHRM2CHRM1CHRM3 | |
| SCHEMBL9667596 | 0.84 | CHRM2 (0.67) | POLBATMCHRM2CHRM1CHRM3 | |
| SCHEMBL30230461 | 0.84 | ATM (1.00) | POLBATMSMN1; SMN2MAPTTSHR | |
| SCHEMBL8635081 | 0.84 | ATM (1.00) | POLBATMSMN1; SMN2MAPTTSHR | |
| SCHEMBL557799 | 0.84 | ATM (1.00) | POLBATMSMN1; SMN2MAPTTSHR | |
| Hydrochloric Acid SCHEMBL3657276 | 0.82 | ATM (0.96) | POLBATMHTR1AHTR1DHTR1B | |
| Iodide SCHEMBL8828192 | 0.82 | ATM (0.96) | POLBATMSMN1; SMN2MAPTTSHR | |
| Hydrochloric Acid SCHEMBL11286388 | 0.82 | HTR2A (0.54) | POLBATMHTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL11561651 | 0.81 | POLB (0.47) | POLBATMSMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |