Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620497 | 0.89 | ZDHHC7 (0.62) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL1415326 | 0.87 | ZDHHC7 (0.59) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9714798 | 0.86 | ZDHHC7 (0.51) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL28979206 | 0.86 | ZDHHC7 (0.51) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9489696 | 0.86 | ZDHHC7 (0.51) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL10929023 | 0.86 | ZDHHC7 (0.51) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL27750312 | 0.84 | KMT2A (0.50) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9548556 | 0.83 | ZDHHC7 (0.72) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL1007430 | 0.83 | ZDHHC7 (0.72) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL4704070 | 0.83 | ZDHHC7 (0.72) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006353-B1 | PROSTAGLANDIN ANALOGUE IMIDAZOLE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1982-08-04 | — | — | EP | disclosed |
| US-4241074-A | BRONCHODILATORS | BEECHAM GROUP LIMITED (GB) | 1980-12-23 | — | — | US | disclosed |
| EP-0006353-A1 | Prostaglandin analogue imidazole derivatives, a process for their preparation and a pharmaceutical composition containing them | BEECHAM GROUP PLC (GB) | 1980-01-09 | — | — | EP | disclosed |