Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.52 |
| ▸ | PGR | P06401 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277487 | 0.93 | NR1I2 (0.53) | NR1I2PGRTDP1LMNAAPAF1 | |
| SCHEMBL11274639 | 0.93 | NR1I2 (0.59) | NR1I2PGRTDP1LMNAL3MBTL1 | |
| SCHEMBL11281007 | 0.89 | NR1I2 (0.66) | NR1I2PGRTDP1LMNAAPAF1 | |
| SCHEMBL11268511 | 0.88 | NR1I2 (0.59) | NR1I2PGRTDP1LMNAL3MBTL1 | |
| SCHEMBL11268025 | 0.87 | NR1I2 (0.58) | NR1I2PGRTDP1LMNAL3MBTL1 | |
| SCHEMBL11272069 | 0.87 | NR1I2 (0.56) | NR1I2PGRTDP1TSHRAPEX1 | |
| SCHEMBL11268186 | 0.86 | NR1I2 (0.54) | NR1I2PGRTDP1LMNAL3MBTL1 | |
| SCHEMBL11265997 | 0.86 | NR1I2 (0.56) | NR1I2PGRTDP1LMNATSHR | |
| SCHEMBL11278235 | 0.86 | NR1I2 (0.66) | NR1I2PGRTDP1LMNAAPAF1 | |
| SCHEMBL11287238 | 0.85 | NR1I2 (0.65) | NR1I2PGRTDP1LMNAAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358448-A | ANTIBIOTICS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-11-09 | — | — | US | claimed |
| US-4358448-A | ANTIBIOTICS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-11-09 | — | — | US | disclosed |