Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL11285437 | 0.88 | MAPT (0.51) | MAPTKMT2AMEN1HTTALDH1A1 | |
| Pyrrolidine SCHEMBL11276989 | 0.78 | MAPT (0.54) | MAPTKMT2AMEN1HTTALDH1A1 | |
| Piperidine SCHEMBL11276780 | 0.78 | MAPT (0.53) | MAPTKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL8036552 | 0.75 | MAPT (0.63) | MAPTKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL8036557 | 0.75 | MAPT (0.63) | MAPTKMT2AMEN1HTTALDH1A1 | |
| Dimethylamine SCHEMBL11274153 | 0.71 | MAPT (0.58) | MAPTKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL8034745 | 0.69 | MAPT (0.68) | MAPTKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL8034748 | 0.69 | MAPT (0.68) | MAPTKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL6662355 | 0.69 | MAPT (0.41) | MAPTKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL6662351 | 0.69 | MAPT (0.41) | MAPTKMT2AMEN1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320125-A | Thiazolylidene-oxo-propionitrile salts and insecticidal compositions containing these salts | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-03-16 | — | — | US | claimed |