Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.41 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.41 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585941 | 0.84 | KMT2A (0.41) | KMT2AMEN1NPSR1NPC1TET3 | |
| SCHEMBL11279736 | 0.84 | KMT2A (0.41) | KMT2AMEN1NPC1TET3FBXL19 | |
| SCHEMBL11280832 | 0.71 | KMT2A (0.47) | KMT2AMEN1NPSR1NPC1TET3 | |
| SCHEMBL4342214 | 0.70 | KMT2A (0.68) | KMT2AMEN1NPSR1NPC1TET3 | |
| SCHEMBL10933849 | 0.70 | KMT2A (0.46) | KMT2AMEN1NPC1TET3FBXL19 | |
| SCHEMBL10800728 | 0.69 | KMT2A (0.45) | KMT2AMEN1NPSR1NPC1TET3 | |
| SCHEMBL11232365 | 0.68 | KMT2A (0.73) | KMT2AMEN1NPSR1TET3FBXL19 | |
| Hydrochloric Acid SCHEMBL10806927 | 0.68 | KMT2A (0.44) | KMT2AMEN1NPSR1NPC1TET3 | |
| SCHEMBL11275114 | 0.67 | KMT2A (0.46) | KMT2AMEN1NPC1TET3FBXL19 | |
| SCHEMBL2357783 | 0.67 | KMT2A (0.46) | KMT2AMEN1NPSR1NPC1TET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309350-A | CONDENSATION OF PHENYLACETIC ESTER WITH DIALKYL OXALATE IN PRESENCE OF BASIC CATALYST, ACIDIFICATION, HYDROXYMETHYLATION, DEHYDRATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1982-01-05 | — | — | US | disclosed |
| US-4262014-A | Insecticidal esters | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1981-04-14 | — | — | US | disclosed |
| US-4220591-A | Insecticidal esters | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1980-09-02 | — | — | US | disclosed |