Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | FAP | Q12884 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.51 |
| ▸ | APEX1 | P27695 | 3/20 | 0.51 |
| ▸ | APAF1 | O14727 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.51 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280885 | 1.00 | PTGS1 (0.65) | PTGS1MAPTFAPALDH1A1USP2 | |
| SCHEMBL9481374 | 0.92 | PTGS1 (0.63) | PTGS1MAPTFAPALDH1A1USP2 | |
| SCHEMBL10345860 | 0.92 | PTGS1 (0.63) | PTGS1MAPTFAPALDH1A1USP2 | |
| SCHEMBL9481364 | 0.92 | PTGS1 (0.63) | PTGS1MAPTFAPALDH1A1USP2 | |
| SCHEMBL10345862 | 0.92 | PTGS1 (0.63) | PTGS1MAPTFAPALDH1A1USP2 | |
| SCHEMBL11277705 | 0.89 | PTGS1 (0.73) | PTGS1MAPTFAPALDH1A1USP2 | |
| SCHEMBL11277715 | 0.89 | PTGS1 (0.73) | PTGS1MAPTFAPALDH1A1USP2 | |
| SCHEMBL10875895 | 0.89 | TDP1 (0.62) | MAPTALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL11285168 | 0.87 | TDP1 (0.56) | MAPTALDH1A1TDP1APEX1APAF1 | |
| SCHEMBL11282014 | 0.87 | TDP1 (0.56) | MAPTALDH1A1TDP1APEX1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048915-A2 | New cephem compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |