Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.56 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273615 | 0.99 | SPHK1 (0.58) | SPHK1SPHK2RARBTSHRHSD17B10 | |
| SCHEMBL11283870 | 0.99 | SPHK1 (0.58) | SPHK1SPHK2RARBTSHRHSD17B10 | |
| SCHEMBL11285655 | 0.99 | SPHK1 (0.58) | SPHK1SPHK2RARBTSHRHSD17B10 | |
| SCHEMBL11277634 | 0.99 | SPHK1 (0.58) | SPHK1SPHK2RARBTSHRHSD17B10 | |
| SCHEMBL11296679 | 0.99 | SPHK1 (0.58) | SPHK1SPHK2RARBTSHRHSD17B10 | |
| SCHEMBL11282240 | 0.99 | SPHK1 (0.58) | SPHK1SPHK2RARBTSHRHSD17B10 | |
| SCHEMBL11276092 | 0.99 | SPHK1 (0.58) | SPHK1SPHK2RARBTSHRHSD17B10 | |
| SCHEMBL11277639 | 0.96 | SPHK1 (0.50) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL11278806 | 0.91 | SPHK1 (0.43) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL9498985 | 0.88 | SPHK1 (0.62) | SPHK1SPHK2HRH3RARBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330426-A | Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0022183-A2 | Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements | MERCK PATENT GmbH (DE) | 1981-01-14 | — | — | EP | disclosed |