Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.67 |
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
| ▸ | CASP5 | P51878 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284926 | 0.86 | HTR2A (0.67) | HTR2CPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10512778 | 0.81 | HTR2C (0.68) | HTR2CHTR2AHRH1USP2SMN1; SMN2 | |
| SCHEMBL1620638 | 0.81 | HTR2C (0.74) | HTR2CPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11288596 | 0.81 | HTR2C (0.53) | HTR2CPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11393857 | 0.79 | HTR2C (1.00) | HTR2CHTR2AHRH1USP2SMN1; SMN2 | |
| SCHEMBL11283943 | 0.78 | HTR2C (0.52) | HTR2CHTR2ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL11280239 | 0.78 | HTR2C (0.64) | HTR2CHTR2AHRH1USP2SMN1; SMN2 | |
| SCHEMBL11286718 | 0.78 | HTR2A (0.65) | HTR2CHTR2AHRH1USP2SMN1; SMN2 | |
| SCHEMBL11286794 | 0.77 | HTR2C (0.62) | HTR2CPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL11292638 | 0.77 | HTR2C (0.62) | HTR2CHTR2AHRH1USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | claimed |
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |