Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13327059 | 0.82 | MEN1 (0.59) | MEN1KMT2APOLBMAOATDP1 | |
| SCHEMBL10634695 | 0.79 | HDAC8 (0.49) | LMNAPOLBMAOAACHE | |
| SCHEMBL16822116 | 0.77 | POLB (0.59) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL24665898 | 0.73 | CYP1A2 (0.61) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL16822023 | 0.72 | CYP1A2 (0.59) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL11098187 | 0.72 | CYP1A2 (0.59) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL6955745 | 0.72 | CYP1A2 (0.59) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL1520129 | 0.71 | APEX1 (0.62) | LMNAALDH1A1CYP1A2L3MBTL1 | |
| SCHEMBL5286253 | 0.71 | CYP1A2 (0.62) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7274898 | 0.71 | TSHR (0.51) | LMNAMEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363814-A | VASODILATORS AND CNS STIMULANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-12-14 | — | — | US | disclosed |
| US-4271158-A | Vasodilating or antidepressant phenalkanolaminoalkyl-substituted imidazolidinones | BOEHRINGER INGELHEIM GMBH (US) | 1981-06-02 | — | — | US | disclosed |
| US-4215119-A | VASODILATORS, ANTIDEPRESSANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-29 | — | — | US | disclosed |
| US-4154829-A | ANTIDEPRESSANT, VASODILATION | BOEHRINGER INGELHEIM GMBH (DE) | 1979-05-15 | — | — | US | disclosed |