Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GALR3 | O60755 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105605 | 0.97 | MAPT (0.38) | MAPTKDM4EPOLBRECQLSMN1; SMN2 | |
| SCHEMBL11105570 | 0.93 | SKP2 (0.39) | MAPTKDM4EPOLBRECQLSMN1; SMN2 | |
| SCHEMBL11107908 | 0.93 | S1PR2 (0.39) | MAPTKDM4EPOLBRECQLSMN1; SMN2 | |
| SCHEMBL11102915 | 0.92 | S1PR2 (0.40) | MAPTKDM4EPOLBSMN1; SMN2MEN1 | |
| SCHEMBL11280160 | 0.91 | S1PR2 (0.41) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL11284023 | 0.91 | S1PR2 (0.41) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL11289581 | 0.91 | S1PR2 (0.41) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL11108210 | 0.91 | S1PR2 (0.41) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL11284323 | 0.91 | S1PR2 (0.41) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL11102504 | 0.91 | SKP2 (0.39) | MAPTKDM4EPOLBRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |