Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979754 | 0.83 | EGFR (0.69) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL1387173 | 0.82 | EGFR (0.61) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL3106181 | 0.81 | EGFR (0.57) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL3977060 | 0.81 | EGFR (0.57) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL8200916 | 0.81 | EGFR (0.57) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL3980790 | 0.80 | EGFR (0.54) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| Hydrochloric Acid SCHEMBL4731344 | 0.79 | EGFR (0.56) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL3635988 | 0.79 | EGFR (0.62) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL17508505 | 0.77 | EGFR (0.54) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL4078517 | 0.77 | KDR (0.61) | RAB9ANPC1TSHRL3MBTL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044163-A2 | Quinazolinyloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1982-01-20 | — | — | EP | disclosed |