Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.65 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287948 | 1.00 | SPHK1 (0.65) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL11286935 | 1.00 | SPHK1 (0.65) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL11280688 | 1.00 | SPHK1 (0.65) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL11281542 | 1.00 | SPHK1 (0.65) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL11282996 | 1.00 | SPHK1 (0.65) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL11286366 | 1.00 | SPHK1 (0.65) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL11286979 | 1.00 | SPHK1 (0.65) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL11289224 | 1.00 | SPHK1 (0.65) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL7907393 | 1.00 | SPHK1 (0.65) | SPHK1SPHK2TSHRHSD17B10RARB | |
| SCHEMBL11282890 | 1.00 | SPHK1 (0.65) | SPHK1SPHK2TSHRHSD17B10RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022183-B1 | DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS | MERCK PATENT GmbH (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4330426-A | Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0022183-A2 | Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements | MERCK PATENT GmbH (DE) | 1981-01-14 | — | — | EP | disclosed |