Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 12/20 | 0.48 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288820 | 0.78 | CASR (0.46) | CASRSLC13A5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1431987 | 0.73 | CYP2C9 (0.50) | SMN1; SMN2MEN1KMT2AHTTGAA | |
| SCHEMBL15157817 | 0.72 | CASR (0.50) | CASRNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10573419 | 0.72 | CASR (0.54) | CASRNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL28712666 | 0.72 | CASR (0.49) | CASRSLC13A5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29449583 | 0.72 | CASR (0.52) | CASRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL28710154 | 0.72 | CASR (0.52) | CASRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL16095839 | 0.71 | CASR (0.52) | CASRNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL28618566 | 0.71 | CASR (0.52) | CASRNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL29516977 | 0.71 | CASR (0.52) | CASRNPC1RAB9ASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055248-A1 | Acetic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-06-30 | — | — | EP | disclosed |
| EP-0055248-A1 | Acetic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-06-30 | — | — | EP | disclosed |