Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11500718 | 0.92 | PTPRB (0.34) | MAPTPTPRBPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11289085 | 0.92 | TDP1 (0.35) | MAPTPTPRBPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11138991 | 0.91 | PTPRB (0.34) | MAPTPTPRBPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11292991 | 0.90 | PTPRB (0.34) | MAPTPTPRBPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11408587 | 0.89 | PTPRB (0.34) | MAPTPTPRBPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10767272 | 0.89 | PTPRB (0.35) | MAPTPTPRBPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11132320 | 0.88 | PTPRB (0.34) | MAPTPTPRBPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11398731 | 0.83 | — | — | |
| SCHEMBL10551257 | 0.83 | TDP1 (0.34) | MAPTPTPRBPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10551118 | 0.83 | MAPT (0.36) | MAPTPTPRBPDE3ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053387-A1 | Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-09 | — | — | EP | disclosed |