Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399359 | 0.82 | KDM4E (0.35) | KDM4E | |
| SCHEMBL401226 | 0.80 | PDE1C (0.33) | — | |
| SCHEMBL1130856 | 0.74 | TNK2 (0.34) | — | |
| SCHEMBL2323693 | 0.71 | KDM4E (0.36) | KDM4E | |
| SCHEMBL30449894 | 0.71 | KMT2A (0.40) | — | |
| SCHEMBL594279 | 0.70 | PDE1C (0.38) | — | |
| SCHEMBL16748878 | 0.70 | MAPT (0.46) | KDM4E | |
| SCHEMBL402325 | 0.69 | HPGD (0.50) | KDM4E | |
| SCHEMBL17892665 | 0.68 | PDE1C (0.33) | — | |
| SCHEMBL17892667 | 0.68 | PDE1C (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283020-A1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI Pharmaceuticals, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009143051-A1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |