Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29606824 | 0.83 | KDM4E (0.57) | KDM4ESMN1; SMN2HTTKMT2AALOX15 | |
| SCHEMBL2065531 | 0.83 | KDM4E (0.57) | KDM4ESMN1; SMN2HTTKMT2AALOX15 | |
| SCHEMBL31373871 | 0.81 | KDM4E (0.59) | KDM4ESMN1; SMN2HTTKMT2AALOX15 | |
| SCHEMBL8667320 | 0.81 | KMT2A (0.60) | KDM4ESMN1; SMN2HTTKMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL11289267 | 0.81 | KDM4E (0.55) | KDM4ESMN1; SMN2HTTKMT2AALOX15 | |
| SCHEMBL6299861 | 0.81 | KDM4E (0.63) | KDM4ESMN1; SMN2HTTKMT2AALOX15 | |
| SCHEMBL28253031 | 0.77 | KDM4E (0.51) | KDM4ESMN1; SMN2HTTKMT2AALOX15 | |
| SCHEMBL28246630 | 0.77 | SMN1; SMN2 (0.51) | KDM4ESMN1; SMN2HTTKMT2AALOX15 | |
| SCHEMBL22042997 | 0.76 | KMT2A (0.53) | KDM4ESMN1; SMN2HTTKMT2AALOX15 | |
| SCHEMBL6298553 | 0.76 | KDM4E (0.57) | KDM4ESMN1; SMN2HTTKMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315940-A | Antidiabetic 1-piperidine-sulfonylureas | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |
| US-4282239-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | disclosed |