SCHEMBL11289647

SCHEMBL11289647

CCCCCCCC1CCC(c2ccc(-c3ccc(OC(C)=O)cc3)cc2)CC1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.46
MAPT P10636 3/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
RAB9A P51151 1/20 0.44
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPK1 P28482 1/20 0.39
RARB P10826 3/20 0.39
SPHK1 Q9NYA1 1/20 0.39
DGAT1 O75907 2/20 0.38
GAA P10253 1/20 0.38
LSS P48449 1/20 0.37
SOAT1 P35610 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11285005 1.00 CYP2C9 (0.46) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL11287747 1.00 CYP2C9 (0.46) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL11277629 1.00 CYP2C9 (0.46) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL11282993 1.00 CYP2C9 (0.46) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL11273929 1.00 CYP2C9 (0.46) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL11282941 1.00 CYP2C9 (0.46) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL11137857 0.99 CYP2C9 (0.47) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL11137865 0.99 CYP2C9 (0.47) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL11280024 0.95 CYP2C9 (0.48) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL20805906 0.95 CYP2C9 (0.50) CYP2C9MAPTALDH1A1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022183-B1 DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS MERCK PATENT GmbH (DE) 1982-06-23 EP disclosed
US-4330426-A Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-18 US disclosed
EP-0022183-A2 Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements MERCK PATENT GmbH (DE) 1981-01-14 EP disclosed