Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.50 |
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 4/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292726 | 1.00 | LPAR1 (0.50) | LPAR1LPAR3CETPLPAR2PLA2G10 | |
| SCHEMBL25335565 | 0.88 | LPAR1 (0.67) | LPAR1LPAR3CETPLPAR2 | |
| SCHEMBL30866263 | 0.88 | LPAR1 (0.53) | LPAR1LPAR3CETPLPAR2PLA2G10 | |
| SCHEMBL31069863 | 0.88 | LPAR1 (0.67) | LPAR1LPAR3CETPLPAR2 | |
| SCHEMBL385051 | 0.88 | LPAR1 (0.67) | LPAR1LPAR3CETPLPAR2 | |
| SCHEMBL10604578 | 0.87 | PLA2G10 (0.47) | LPAR1LPAR3CETPLPAR2PLA2G10 | |
| SCHEMBL18641859 | 0.87 | PLA2G10 (0.47) | LPAR1LPAR3CETPLPAR2PLA2G10 | |
| SCHEMBL10605748 | 0.87 | PLA2G10 (0.47) | LPAR1LPAR3CETPLPAR2PLA2G10 | |
| SCHEMBL10604671 | 0.87 | PLA2G10 (0.47) | LPAR1LPAR3CETPLPAR2PLA2G10 | |
| SCHEMBL11319207 | 0.86 | TSHR (0.41) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002062-B1 | CYCLIC ORGANOPHOSPHORUS COMPOUNDS, METHOD FOR THEIR PREPARATION AND THEIR USE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1982-05-05 | — | — | EP | disclosed |
| EP-0002062-A1 | Cyclic organophosphorus compounds, method for their preparation and their use | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1979-05-30 | — | — | EP | disclosed |