Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354573 | 1.00 | CYP3A4 (0.81) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL1128529 | 0.92 | CYP3A4 (0.77) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL9006352 | 0.90 | CYP3A4 (0.79) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL2019784 | 0.90 | CYP3A4 (0.79) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL1128644 | 0.90 | CYP3A4 (1.00) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL1128844 | 0.89 | CYP3A4 (0.84) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL4355890 | 0.89 | CYP3A4 (0.77) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL9007710 | 0.88 | CYP3A4 (0.64) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL4361119 | 0.88 | CYP3A4 (0.75) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL1128902 | 0.88 | CYP3A4 (0.75) | CYP3A4CYP2C9GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283019-A1 | GPR119 RECEPTOR AGONISTS | F. Hoffmann-La Roche AG (CH) | 2011-02-16 | — | — | EP | disclosed |