Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLK1 | O15075 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.56 |
| ▸ | CSF1R | P07333 | 1/20 | 0.56 |
| ▸ | FER | P16591 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | MARK3 | P27448 | 1/20 | 0.56 |
| ▸ | FLT4 | P35916 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.56 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.56 |
| ▸ | STK3 | Q13188 | 1/20 | 0.56 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.56 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129198 | 0.88 | PDPK1 (0.50) | DCLK1PRKD3MAP4K4CHEK2CSF1R | |
| SCHEMBL1129160 | 0.86 | MAP4K4 (0.58) | DCLK1PRKD3MAP4K4CHEK2CSF1R | |
| SCHEMBL6780936 | 0.81 | NTRK1 (0.44) | MAP4K4CDK2AURKBCLK4MKNK2 | |
| SCHEMBL1144803 | 0.80 | PDPK1 (0.54) | DCLK1PRKD3MAP4K4CHEK2CSF1R | |
| SCHEMBL5796193 | 0.78 | ITK (0.48) | CCNCCDK8NTRK1MEN1KMT2A | |
| SCHEMBL8138818 | 0.77 | PDPK1 (0.56) | DCLK1PRKD3MAP4K4CHEK2CSF1R | |
| SCHEMBL22632566 | 0.76 | PDPK1 (0.50) | DCLK1PRKD3MAP4K4CHEK2CSF1R | |
| SCHEMBL182234 | 0.76 | PDPK1 (0.58) | DCLK1PRKD3MAP4K4CHEK2CSF1R | |
| SCHEMBL1271820 | 0.76 | PDPK1 (0.58) | DCLK1PRKD3MAP4K4CHEK2CSF1R | |
| SCHEMBL14338765 | 0.76 | PDPK1 (0.58) | DCLK1PRKD3MAP4K4CHEK2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282742-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | Infinity Pharmaceuticals, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009126691-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC (US) | 2009-10-15 | — | — | WO | disclosed |