Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975284 | 1.00 | HTT (0.40) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL5862504 | 1.00 | HTT (0.40) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL1896640 | 1.00 | HTT (0.40) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL504003 | 0.98 | CYP1A2 (0.41) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL4159832 | 0.93 | CYP1A2 (0.37) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL1893345 | 0.93 | CYP1A2 (0.47) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL8735525 | 0.91 | CYP1A2 (0.36) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL7723142 | 0.90 | CYP1A2 (0.35) | HTTMEN1KMT2ACYP1A2TP53 | |
| SCHEMBL4170126 | 0.88 | CYP1A2 (0.42) | HTTMEN1KMT2ACYP1A2PKM | |
| SCHEMBL6278928 | 0.85 | HPGD (0.34) | KMT2ACYP1A2CYP2C9NAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335011-A | Cyclohexyl-dioxane liquid crystalline compounds | TIMEX CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
| US-4298528-A | FOR ELECTRO-OPTICAL DISPLAYS | TIMEX CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |