Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.43 |
| ▸ | APEX1 | P27695 | 3/20 | 0.43 |
| ▸ | APAF1 | O14727 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282180 | 1.00 | PTGS1 (0.43) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL5672543 | 0.93 | PTGS1 (0.52) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL5672538 | 0.93 | PTGS1 (0.52) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL11283556 | 0.91 | PTGS1 (0.47) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL11283553 | 0.91 | PTGS1 (0.47) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10848834 | 0.88 | NR1I2 (0.46) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10848830 | 0.88 | NR1I2 (0.46) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL9360542 | 0.87 | TDP1 (0.46) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL9360548 | 0.87 | TDP1 (0.46) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10366997 | 0.87 | TDP1 (0.46) | PTGS1ABCB11PDE4DTDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365062-A | BACTERICIDAL ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1982-12-21 | — | — | US | disclosed |
| US-4307230-A | ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |
| US-4307233-A | ANTIBACTERIAL AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |
| US-4307116-A | BACTERICIDES | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |