Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.44 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28252938 | 0.91 | SIRT2 (0.51) | MEN1KMT2AALDH1A1HPGDSIRT2 | |
| SCHEMBL28252935 | 0.91 | SIRT2 (0.51) | MEN1KMT2AALDH1A1HPGDSIRT2 | |
| SCHEMBL10419873 | 0.87 | MEN1 (0.58) | MEN1KMT2AALDH1A1HPGDSIRT2 | |
| SCHEMBL7776611 | 0.87 | MEN1 (0.55) | MEN1KMT2AALDH1A1HPGDSIRT2 | |
| SCHEMBL7776616 | 0.87 | MEN1 (0.55) | MEN1KMT2AALDH1A1HPGDSIRT2 | |
| SCHEMBL17446676 | 0.86 | KMT2A (0.59) | MEN1KMT2AALDH1A1HPGDSIRT2 | |
| SCHEMBL17446749 | 0.83 | SIRT2 (0.46) | MEN1KMT2AALDH1A1HPGDSIRT2 | |
| SCHEMBL5017052 | 0.83 | MEN1 (0.53) | MEN1KMT2AALDH1A1HPGDSIRT2 | |
| SCHEMBL22271575 | 0.83 | MEN1 (0.53) | MEN1KMT2AALDH1A1HPGDSIRT2 | |
| SCHEMBL9838107 | 0.83 | MEN1 (0.53) | MEN1KMT2AALDH1A1HPGDSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362716-A | IMMUNOSTIMULANTS | RHONE-POULENC INDUSTRIES (FR) | 1982-12-07 | — | — | US | claimed |
| US-4362716-A | IMMUNOSTIMULANTS | RHONE-POULENC INDUSTRIES (FR) | 1982-12-07 | — | — | US | disclosed |