⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926626 | 1.00 | — | — | |
| SCHEMBL23355996 | 0.81 | — | — | |
| SCHEMBL3857933 | 0.78 | AKR1B1 (0.37) | — | |
| SCHEMBL1547638 | 0.78 | AKR1B1 (0.37) | — | |
| SCHEMBL23072256 | 0.78 | AKR1B1 (0.37) | — | |
| SCHEMBL31611656 | 0.78 | AKR1B1 (0.37) | — | |
| SCHEMBL79469 | 0.77 | — | — | |
| SCHEMBL27843110 | 0.75 | — | — | |
| SCHEMBL1314284 | 0.75 | — | — | |
| Phosphoric Acid SCHEMBL25339940 | 0.73 | MPI (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282773-B2 | METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION | SEAGEN INC (US) | 2025-03-05 | — | — | EP | disclosed |
| CN-112236438-B | Phosphorus (V) based reagent, method for the production thereof, and use thereof for producing stereoregular organic phosphorus (V) compounds | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112996854-B | High purity PEG lipids and uses thereof | 摩登纳特斯有限公司 | 2024-08-30 | — | — | CN | disclosed |
| US-20240117400-A1 | T CELLS WITH REDUCED SURFACE FUCOSYLATION AND METHODS OF MAKING AND USING THE SAME | SEAGEN INC (US) | 2024-04-11 | — | — | US | disclosed |
| US-11891644-B2 | T cells with reduced surface fucosylation and methods of making and using the same | SEAGEN INC. (US) | 2024-02-06 | — | — | US | disclosed |
| CN-117222422-A | Sanopassing polypeptides and their use in the treatment of cancer | 旗舰创业创新五公司 | 2023-12-12 | — | — | CN | disclosed |
| US-20230055475-A1 | METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION | SEAGEN INC (US) | 2023-02-23 | — | — | US | disclosed |
| CN-115244061-A | Reagents and their use for modular enantioselective synthesis of C-P bonds | 百时美施贵宝公司 | 2022-10-25 | — | — | CN | disclosed |
| US-11319526-B2 | Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation | SEAGEN INC. (US) | 2022-05-03 | — | — | US | disclosed |
| US-20220081477-A1 | CONTROLLED FUCOSYLATION OF ANTIBODIES | SEAGEN INC (US) | 2022-03-17 | — | — | US | disclosed |
| EP-2282773-B1 | METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION | SEATTLE GENETICS INC (US) | 2014-01-15 | — | — | EP | disclosed |
| US-8574907-B2 | Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation | SEATTLE GENETICS, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| EP-2608796-A2 | METHODS OF INHIBITION OF PROTEIN FUCOSYLATION IN VIVO USING FUCOSE ANALOGS | Seattle Genetics, Inc. (US) | 2013-07-03 | — | — | EP | disclosed |
| US-20130129784-A1 | METHODS OF INHIBITION OF PROTEIN FUCOSYLATION IN VIVO USING FUCOSE ANALOGS | SEATTLE GENETICS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20120183997-A1 | METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION | SEATTLE GENETICS, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| US-8163551-B2 | Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation | SEATTLE GENETICS, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| WO-2012019165-A2 | METHODS OF INHIBITION OF PROTEIN FUCOSYLATION IN VIVO USING FUCOSE ANALOGS | SEATTLE GENETICS, INC. (US) | 2012-02-09 | — | — | WO | disclosed |
| EP-2282773-A2 | METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION | Seattle Genetics, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| US-20090317869-A1 | METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION | SEATTLE GENETICS, INC. (US) | 2009-12-24 | — | — | US | disclosed |
| WO-2009135181-A2 | METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION | SEATTLE GENETICS, INC. (US) | 2009-11-05 | — | — | WO | disclosed |