Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MMP16 | P51512 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291687 | 1.00 | HAO1 (0.50) | HAO1HTTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11292309 | 1.00 | HAO1 (0.50) | HAO1HTTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11295179 | 0.99 | HTT (0.51) | HAO1HTTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11293026 | 0.99 | HTT (0.51) | HAO1HTTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11296495 | 0.99 | HTT (0.51) | HAO1HTTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11292881 | 0.97 | HAO1 (0.48) | HAO1HTTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11296740 | 0.97 | HAO1 (0.48) | HAO1HTTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11302882 | 0.97 | HAO1 (0.48) | HAO1HTTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11295223 | 0.97 | HAO1 (0.48) | HAO1HTTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11292210 | 0.96 | HAO1 (0.49) | HAO1HTTTDP1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356325-A | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-26 | — | — | US | disclosed |