SCHEMBL11292561

SCHEMBL11292561

CC=Cc1ccccc1.[KH]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.55
LMNA P02545 3/20 0.48
ALDH1A1 P00352 3/20 0.48
CHAT P28329 2/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
TSHR P16473 1/20 0.48
KDM4E B2RXH2 1/20 0.48
TRPA1 O75762 2/20 0.46
RELA Q04206 1/20 0.46
GLA P06280 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
NFE2L2 Q16236 1/20 0.46
CYP19A1 P11511 1/20 0.46
MAOA P21397 1/20 0.46
ALOX5 P09917 1/20 0.46
MAPK1 P28482 1/20 0.46
HDAC3 O15379 1/20 0.44
TNKS O95271 1/20 0.44
HDAC4 P56524 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL1225180 0.97 MAOB (0.58) MAOBLMNAALDH1A1CHATTP53
Benzene SCHEMBL1225177 0.97 MAOB (0.58) MAOBLMNAALDH1A1CHATTP53
SCHEMBL671163 0.97 MAOB (0.58) MAOBLMNAALDH1A1CHATTP53
SCHEMBL2342 0.97
SCHEMBL28967 0.97
SCHEMBL335864 0.97
Iodide SCHEMBL9023356 0.94 MAOB (0.55) MAOBLMNAALDH1A1CHATTP53
Hydrochloric Acid SCHEMBL498589 0.94 MAOB (0.55) MAOBLMNAALDH1A1CHATTP53
Water SCHEMBL10386353 0.94 MAOB (0.55) MAOBLMNAALDH1A1CHATTP53
SCHEMBL5049484 0.94 MAOB (0.55) MAOBLMNAALDH1A1CHATTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4224429-A CROWN COMPOUNDS SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1980-09-23 US claimed
US-4116887-A OF HETEROCYCLIC MONOMERS BY RING OPENING, MACROHETEROCYCLIC COMPLEXING AGENTS SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1978-09-26 US claimed
US-4362837-A NEUTRALIZATION OF ACID END GROUPS UNIBRA SOCIETE ANONYME (BE) 1982-12-07 US disclosed
US-4116887-A OF HETEROCYCLIC MONOMERS BY RING OPENING, MACROHETEROCYCLIC COMPLEXING AGENTS SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1978-09-26 US disclosed