Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28618729 | 1.00 | PLA2G2C (0.49) | PLA2G2CGPR84FFAR1MAPTLCK | |
| SCHEMBL6154715 | 1.00 | PLA2G2C (0.49) | PLA2G2CGPR84FFAR1MAPTLCK | |
| SCHEMBL27992370 | 1.00 | PLA2G2C (0.49) | PLA2G2CGPR84FFAR1MAPTLCK | |
| SCHEMBL11168552 | 1.00 | PLA2G2C (0.49) | PLA2G2CGPR84FFAR1MAPTLCK | |
| SCHEMBL27793369 | 1.00 | PLA2G2C (0.49) | PLA2G2CGPR84FFAR1MAPTLCK | |
| SCHEMBL529507 | 0.98 | PLA2G2C (0.46) | PLA2G2CGPR84FFAR1MAPTLCK | |
| Hydrochloric Acid SCHEMBL28811673 | 0.96 | PLA2G2C (0.45) | PLA2G2CGPR84FFAR1MAPTLCK | |
| SCHEMBL20459159 | 0.92 | PLA2G2C (0.56) | PLA2G2CGPR84FFAR1MAPTLCK | |
| SCHEMBL20459227 | 0.92 | PLA2G2C (0.56) | PLA2G2CGPR84FFAR1MAPTLCK | |
| SCHEMBL9097264 | 0.92 | PLA2G2C (0.56) | PLA2G2CGPR84FFAR1MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563103-B | Modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-111699189-A | Modulators of beta-3 adrenergic receptors useful for the treatment or prevention of heart failure and disorders associated therewith | 艾尼纳制药公司 | 2020-09-22 | — | — | CN | disclosed |
| US-4336402-A | Process for the preparation of N-alkyl-monosubstituted carbamic acid esters | ATLANTIC RICHFIELD COMPANY (US) | 1982-06-22 | — | — | US | disclosed |