SCHEMBL1129367

SCHEMBL1129367

Cc1cc(S)ccc1-c1ccccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.47
NPC1 O15118 5/20 0.47
LMNA P02545 3/20 0.45
CCR1 P32246 3/20 0.45
CCR5 P51681 3/20 0.45
CCR8 P51685 3/20 0.45
METAP1 P53582 2/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
BLM P54132 1/20 0.45
HIF1A Q16665 1/20 0.45
DOHH Q9BU89 1/20 0.45
P4HTM Q9NXG6 1/20 0.45
TGFBR1 P36897 1/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
RAB9A P51151 3/20 0.40
PKM P14618 2/20 0.40
MITF O75030 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4550924 0.81 KDM4E (0.50) KDM4ENPC1LMNACCR1CCR5
SCHEMBL29901536 0.81 KDM4E (0.50) KDM4ENPC1LMNACCR1CCR5
SCHEMBL17427076 0.81 KDM4E (0.57) KDM4ENPC1LMNACCR1CCR5
SCHEMBL13581443 0.79 KDM4E (0.55) KDM4ENPC1LMNACCR1CCR5
SCHEMBL30776779 0.79 KDM4E (0.55) KDM4ENPC1LMNACCR1CCR5
SCHEMBL4337894 0.79 NPC1 (0.50) KDM4ENPC1LMNACCR1CCR5
SCHEMBL4550928 0.79 KDM4E (0.47) KDM4ENPC1LMNACCR1CCR5
SCHEMBL17306381 0.79 KDM4E (0.47) KDM4ENPC1LMNACCR1CCR5
SCHEMBL30090683 0.79 KDM4E (0.47) KDM4ENPC1LMNACCR1CCR5
SCHEMBL18633527 0.77 KDM4E (0.46) KDM4ENPC1LMNACCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952256-B1 METHOD FOR THE PRODUCTION OF CATALYSTS LANXESS DEUTSCHLAND GMBH (DE) 2017-05-17 EP disclosed
EP-2952256-A1 METHOD FOR THE PRODUCTION OF CATALYSTS LANXESS Deutschland GmbH (DE) 2015-12-09 EP disclosed
US-8932976-B2 Preparation of catalyst for bisphenols production DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-13 US disclosed
EP-2158040-B1 PREPARATION OF CATALYST FOR BISPHENOLS PRODUCTION DOW GLOBAL TECHNOLOGIES INC (US) 2011-02-16 EP disclosed
US-20100152028-A1 PREPARATION OF CATALYST FOR BISPHENOLS PRODUCTION DOW GLOBAL TECHNOLOGIES LLC 2010-06-17 US disclosed
CN-101678354-A The Preparation of catalysts that is used for bisphenol production DOW GLOBAL TECHNOLOGIES INC 2010-03-24 CN disclosed
EP-2158040-A1 PREPARATION OF CATALYST FOR BISPHENOLS PRODUCTION Dow Global Technologies Inc. (US) 2010-03-03 EP disclosed
WO-2008157025-A1 PREPARATION OF CATALYST FOR BISPHENOLS PRODUCTION DOW GLOBAL TECHNOLOGIES INC. (US) 2008-12-24 WO disclosed