Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 5/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769245 | 0.90 | RAF1 (0.50) | RAF1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL1011493 | 0.89 | RAF1 (0.49) | RAF1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL769541 | 0.87 | RAF1 (0.64) | RAF1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL770045 | 0.85 | RAF1 (0.50) | RAF1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL1015499 | 0.85 | RAF1 (0.52) | RAF1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL19350709 | 0.83 | RAF1 (0.47) | RAF1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL1012213 | 0.83 | RAF1 (0.48) | RAF1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL1015351 | 0.82 | RAF1 (0.50) | RAF1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL770136 | 0.82 | RAF1 (0.46) | RAF1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL11966207 | 0.82 | RAF1 (0.47) | RAF1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044185-A2 | Imidazolidinone derivatives | ELI LILLY AND COMPANY (US) | 1982-01-20 | — | — | EP | disclosed |