Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28765737 | 0.95 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL5958589 | 0.89 | TSHR (0.61) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL30018303 | 0.89 | TSHR (0.61) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL27615 | 0.89 | TSHR (0.61) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL284717 | 0.89 | TSHR (0.61) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL10877779 | 0.89 | TSHR (0.61) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL9225652 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| Water SCHEMBL10623226 | 0.88 | TSHR (0.59) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| Ammonia Solution, Strong SCHEMBL14915113 | 0.88 | TSHR (0.59) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL18171320 | 0.88 | TSHR (0.59) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094537-B1 | AIRBAG AND PROCESS FOR ITS ASSEMBLY | DOW CORNING (US) | 2013-02-27 | — | — | EP | disclosed |
| US-8287685-B2 | Airbag and process for its assembly | DOW CORNING CORPORATION (US) | 2012-10-16 | — | — | US | disclosed |
| US-20110076479-A1 | Process And Composition For Fabricating Non-Sewn Seams | DOW CORNING CORPORATION | 2011-03-31 | — | — | US | disclosed |
| EP-2283095-A2 | PROCESS AND COMPOSITION FOR FABRICATING NON-SEWN SEAMS | Dow Corning Corporation (US) | 2011-02-16 | — | — | EP | disclosed |
| US-20100015407-A1 | Airbag and Process for its Assembly | DOW CORNING CORPORATION | 2010-01-21 | — | — | US | disclosed |
| WO-2009143090-A2 | PROCESS AND COMPOSITION FOR FABRICATING NON-SEWN SEAMS | DOW CORNING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |
| EP-2094537-A1 | AIRBAG AND PROCESS FOR ITS ASSEMBLY | Dow Corning Corporation (US) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008069856-A1 | AIRBAG AND PROCESS FOR ITS ASSEMBLY | DOW CORNING CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |