Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198006 | 0.67 | KMT2A (0.35) | KDM4EMEN1GMNNLMNAPMP22 | |
| SCHEMBL9724656 | 0.67 | POLB (0.33) | KDM4EMEN1GMNNLMNAPMP22 | |
| SCHEMBL9653099 | 0.67 | POLB (0.33) | KDM4EMEN1GMNNLMNAPMP22 | |
| SCHEMBL6626660 | 0.63 | KDM4E (0.37) | TACR1KDM4ETDP1 | |
| SCHEMBL12763442 | 0.63 | SLC1A2 (0.41) | KDM4EMEN1GMNNLMNAPMP22 | |
| SCHEMBL1616764 | 0.63 | SLC18A3 (0.33) | KDM4E | |
| SCHEMBL12226905 | 0.63 | POLB (0.48) | KDM4EGMNNLMNAPMP22KMT2A | |
| SCHEMBL16909909 | 0.63 | POLB (0.48) | KDM4EGMNNLMNAPMP22KMT2A | |
| SCHEMBL4968055 | 0.63 | POLB (0.48) | KDM4EGMNNLMNAPMP22KMT2A | |
| SCHEMBL967161 | 0.63 | POLB (0.48) | KDM4EGMNNLMNAPMP22TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292190-A | ANTIFREEZES FOR COOLING SYSTEMS OF INTERNAL COMBUSTION ENGINES | BASF WYANDOTTE CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |