SCHEMBL11295441

SCHEMBL11295441

C#Cc1ccc(Oc2ccc(S(=O)(=O)c3ccc(Oc4cccc(Oc5ccc(S(=O)(=O)c6ccc(Oc7ccc(C#C)cc7)cc6)cc5)c4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.50
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
CA4 P22748 1/20 0.44
SOS1 Q07889 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.42
MITF O75030 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
GFER P55789 1/20 0.42
KMT2A Q03164 1/20 0.42
NLRP1 Q9C000 1/20 0.42
NOD2 Q9HC29 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11294966 1.00 HTT (0.56) HTTL3MBTL1TDP1SMN1; SMN2CA12
SCHEMBL11299821 1.00 HTT (0.56) HTTL3MBTL1TDP1SMN1; SMN2CA12
SCHEMBL11298929 0.95 HTT (0.52) HTTL3MBTL1TDP1SMN1; SMN2CA12
SCHEMBL11299216 0.95 HTT (0.52) HTTL3MBTL1TDP1SMN1; SMN2CA12
SCHEMBL11298662 0.95 HTT (0.52) HTTL3MBTL1TDP1SMN1; SMN2CA12
SCHEMBL11293336 0.95 HTT (0.52) HTTL3MBTL1TDP1SMN1; SMN2CA12
SCHEMBL11301110 0.94 HTT (0.54) HTTL3MBTL1TDP1SMN1; SMN2CA12
SCHEMBL11298696 0.94 HTT (0.54) HTTL3MBTL1TDP1SMN1; SMN2CA12
SCHEMBL11298933 0.94 HTT (0.54) HTTL3MBTL1TDP1SMN1; SMN2CA12
SCHEMBL11294599 0.92 HTT (0.55) HTTL3MBTL1TDP1SMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4356325-A Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-10-26 US disclosed