Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792299 | 0.89 | TDP1 (0.50) | TDP1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL10790924 | 0.88 | TDP1 (0.49) | TDP1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL11292712 | 0.86 | TDP1 (0.68) | TDP1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL10792101 | 0.85 | BRD4 (0.47) | TDP1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL11294769 | 0.82 | TDP1 (0.53) | TDP1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL11292990 | 0.80 | TDP1 (0.51) | TDP1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL11289075 | 0.80 | TDP1 (0.51) | TDP1CYP1A2CYP2D6CYP2C19LMNA | |
| Iodide SCHEMBL29037976 | 0.79 | TDP1 (0.61) | TDP1CYP1A2CYP2D6CYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL28192676 | 0.79 | TDP1 (0.61) | TDP1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL698581 | 0.78 | TDP1 (0.49) | TDP1CYP1A2CYP2D6CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064820-A1 | Substituted imidazole and imidazoline derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1982-11-17 | — | — | EP | disclosed |