Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.68 |
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11406573 | 0.90 | KMT2A (0.59) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL11659558 | 0.89 | MAPT (0.64) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL2776809 | 0.89 | MAPT (0.57) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL11631142 | 0.89 | KMT2A (0.58) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL11629149 | 0.86 | KMT2A (0.55) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL11630189 | 0.86 | KMT2A (0.55) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL16742373 | 0.86 | MAPT (0.60) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL6525254 | 0.85 | MAPT (0.62) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL8346764 | 0.85 | KMT2A (0.54) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL9819650 | 0.85 | KMT2A (0.54) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054228-A1 | Process for the preparation of 1-amino 2 or 4 nitro-alkoxy benzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-23 | — | — | EP | claimed |
| EP-0054228-A1 | Process for the preparation of 1-amino 2 or 4 nitro-alkoxy benzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-23 | — | — | EP | disclosed |