SCHEMBL1129620

SCHEMBL1129620

O=C(OCCCc1ccccc1)c1ccc(O)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.82
ESR2 Q92731 1/20 0.82
LMNA P02545 3/20 0.68
SMN1; SMN2 Q16637 3/20 0.61
TSHR P16473 2/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2D6 P10635 1/20 0.61
MAPK1 P28482 1/20 0.61
CYP2C19 P33261 1/20 0.61
NR1H2 P55055 1/20 0.61
RNASEL Q05823 1/20 0.61
TDP1 Q9NUW8 3/20 0.61
NPC1 O15118 3/20 0.60
RAB9A P51151 3/20 0.60
AKR1B10 O60218 1/20 0.59
AKR1B1 P15121 1/20 0.59
DPP4 P27487 1/20 0.58
MAPT P10636 1/20 0.56
SLC6A2 P23975 2/20 0.56
ALDH1A1 P00352 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6392668 0.95 ESR1 (0.75) ESR1ESR2LMNASMN1; SMN2TSHR
SCHEMBL31678922 0.92 ESR1 (0.68) ESR1ESR2LMNASMN1; SMN2TSHR
SCHEMBL1129589 0.90 ESR1 (1.00) ESR1ESR2LMNASMN1; SMN2TSHR
SCHEMBL839075 0.90 TDP1 (0.75) ESR1ESR2LMNASMN1; SMN2MAPK1
SCHEMBL28714878 0.87 TDP1 (0.70) ESR1ESR2LMNATDP1NPC1
SCHEMBL5153066 0.86 TDP1 (0.81) ESR1ESR2LMNASMN1; SMN2TSHR
SCHEMBL5152566 0.86 TDP1 (0.75) ESR1ESR2LMNASMN1; SMN2TSHR
SCHEMBL5152874 0.86 ESR1 (0.80) ESR1ESR2LMNASMN1; SMN2TSHR
SCHEMBL6397452 0.86 ESR1 (0.91) ESR1ESR2LMNASMN1; SMN2TSHR
SCHEMBL5155759 0.85 TDP1 (0.79) ESR1ESR2LMNASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021232060-A1 SCENTED COLOR-CHANGING SYSTEM AKI, INC. (US) 2021-11-18 WO disclosed
US-20210353815-A1 SCENTED COLOR-CHANGING SYSTEM AKI, INC. (US) 2021-11-18 US disclosed
US-10953129-B2 Wetness indicator compositions comprising leuco dyes Savarè I.C. S.r.l. (IT) 2021-03-23 US disclosed
EP-2756295-B1 WETNESS INDICATOR HAVING VARIED HUES KIMBERLY CLARK CO (US) 2020-10-07 EP disclosed
EP-2782537-B1 NON-TACKY WETNESS INDICATOR COMPOSITION FOR APPLICATION ON A POLYMERIC SUBSTRATE KIMBERLY CLARK CO (US) 2018-11-07 EP disclosed
EP-2775976-B1 AQUEOUS MEDIUM-SENSITIVE COATING COMPOSITIONS FOR TRIGGERED RELEASE OF ACTIVE INGREDIENTS AND VISUAL INDICATION FOR WETNESS KIMBERLY CLARK CO (US) 2018-05-30 EP disclosed
US-20180110896-A1 WETNESS INDICATOR COMPOSITIONS COMPRISING LEUCO DYES Savarè I.C. S.r.l. (IT) 2018-04-26 US disclosed
EP-2890413-B1 A COLOR-CHANGING COMPOSITION AND MATERIAL KIMBERLY CLARK CO (US) 2018-04-04 EP disclosed
EP-3283133-A1 WETNESS INDICATOR COMPOSITIONS COMPRISING LEUCO DYES Savare' I.c. S.r.l. (IT) 2018-02-21 EP disclosed
US-9889222-B2 Aqueous medium-sensitive coating compositions for triggered release of active ingredients and visual indication for wetness KIMBERLY-CLARK WORLDWIDE, INC. (US) 2018-02-13 US disclosed
US-4580153-A COLOR FORMING BETWEEN COLORLESS CHROMOGENIC VINYL PHTHALIDE COMPOUND AND ELECTRON ACCEPTOR KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1986-04-01 US disclosed
US-4558335-A BENZYL 4-BENZYLOXYBENZOATE, CHROMOGEN AND PHENOLIC COMPOUND YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1985-12-10 US disclosed
EP-0155593-A2 Fluoran compounds and recording sheets containing them KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1985-09-25 EP disclosed
US-4539225-A SMOTHING BETWEEN METAL AND ELASTIC ROLLS KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1985-09-03 US disclosed
US-4531140-A Heat-sensitive recording material Kansaki Paper Manufacturing Co. Ltd. (JP) 1985-07-23 US disclosed
EP-0059975-B1 THERMORESPONSIVE RECORDING SHEET Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1985-06-26 EP disclosed
US-4523205-A COLORLESS BASIC DYE AND DEVELOPER KANZAKI PAPER MFG. CO., LTD. (JP) 1985-06-11 US disclosed
EP-0141170-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-05-15 EP disclosed
EP-0131631-A1 HEAT-SENSITIVE RECORDING PAPER Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1985-01-23 EP disclosed
EP-0059975-A1 Thermoresponsive recording sheet Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1982-09-15 EP disclosed