SCHEMBL1129693

SCHEMBL1129693

O=C(Cc1ccccc1)Nc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 3/20 0.61
MCL1 Q07820 1/20 0.61
EPHX2 P34913 1/20 0.60
KMT2A Q03164 4/20 0.57
ALDH1A1 P00352 3/20 0.57
MEN1 O00255 3/20 0.57
KDM4E B2RXH2 2/20 0.57
MAPT P10636 1/20 0.57
LMNA P02545 2/20 0.56
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
GAA P10253 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.55
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6580500 0.88 EPHX2 (0.57) EPHX2KMT2AALDH1A1MEN1KDM4E
SCHEMBL1130032 0.88 KMT2A (0.61) KDM4CMCL1EPHX2KMT2AALDH1A1
SCHEMBL8748442 0.87 KMT2A (0.60) KDM4CMCL1EPHX2KMT2AALDH1A1
SCHEMBL29614981 0.85 MAPT (0.66) KDM4CMCL1ALDH1A1KDM4EMAPT
SCHEMBL10759415 0.85 PSMB8 (0.55) KDM4CMCL1ALDH1A1KDM4E
SCHEMBL28194953 0.81 MCL1 (0.57) MCL1EPHX2KMT2AALDH1A1MEN1
SCHEMBL17615834 0.80 KDM4C (0.66) KDM4CEPHX2KMT2AALDH1A1MEN1
SCHEMBL29045182 0.80 KDM4C (0.66) KDM4CEPHX2KMT2AALDH1A1MEN1
SCHEMBL30516127 0.80 KDM4C (0.66) KDM4CEPHX2KMT2AALDH1A1MEN1
SCHEMBL8857854 0.80 KDM4C (0.66) KDM4CEPHX2KMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283287-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-10-09 US disclosed
EP-2036737-B1 Thermosensitive recording material RICOH CO LTD (JP) 2011-02-16 EP disclosed
US-20090075817-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-03-19 US disclosed
EP-2036737-A1 Thermosensitive recording material Ricoh Company, Ltd. (JP) 2009-03-18 EP disclosed