Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525808 | 0.85 | CTSA (0.40) | CTSAACHE | |
| SCHEMBL331812 | 0.83 | PPARD (0.58) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL12808336 | 0.77 | TSHR (0.40) | TSHRPPARDCTSAACHETP53 | |
| SCHEMBL10394484 | 0.77 | TSHR (0.48) | TSHRPPARDCTSAACHETP53 | |
| SCHEMBL19380267 | 0.77 | TSHR (0.48) | TSHRPPARDCTSAACHETP53 | |
| SCHEMBL2482314 | 0.75 | PPARD (0.50) | TSHRPPARDCTSAACHETP53 | |
| SCHEMBL2320788 | 0.72 | CTSA (0.37) | CTSAACHE | |
| SCHEMBL11443316 | 0.71 | TSHR (0.46) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL5751910 | 0.71 | CTSA (0.36) | CTSAACHE | |
| SCHEMBL525701 | 0.71 | CTSA (0.43) | CTSAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293505-A | Preparation of β-haloethylphosphonic acids and half esters thereof | GAF CHEMICALS CORPORATION | 1981-10-06 | — | — | US | disclosed |