SCHEMBL11298536

SCHEMBL11298536

CC1CC(c2ccccc2Br)c2cccc(Br)c21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 6/20 0.45
HTR2B P41595 6/20 0.45
HTR2A P28223 4/20 0.45
HRH3 Q9Y5N1 2/20 0.45
KDM1A O60341 2/20 0.42
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 1/20 0.38
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
RCOR1 Q9UKL0 1/20 0.35
BRD4 O60885 1/20 0.35
DRD1 P21728 2/20 0.35
DRD5 P21918 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11294214 0.83 HTR2C (0.49) HTR2CHTR2BHTR2AHRH3KDM1A
SCHEMBL11308474 0.78 HTR2C (0.42) HTR2CHTR2BHTR2AHRH3KDM1A
SCHEMBL16349688 0.74 HTR2C (0.34) HTR2CHTR2BHTR2AKDM1ASLC6A2
SCHEMBL11292597 0.71 HTR2C (0.46) HTR2CHTR2BHTR2AHRH3LMNA
SCHEMBL21197732 0.69 KDM1A (0.47) HTR2CHTR2BHTR2AHRH3KDM1A
SCHEMBL30525107 0.69 KDM1A (0.47) HTR2CHTR2BHTR2AHRH3KDM1A
SCHEMBL11295269 0.69 HTR2A (0.46) HTR2CHTR2BHTR2AHRH3KDM1A
SCHEMBL12876076 0.69 KDM1A (0.61) HTR2CHTR2BHTR2AHRH3KDM1A
SCHEMBL31172423 0.69 KDM1A (0.61) HTR2CHTR2BHTR2AHRH3KDM1A
SCHEMBL21197740 0.68 HTR2C (0.45) HTR2CHTR2BHTR2AHRH3KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0004591-B1 SHELL CATALYST, PROCESS FOR ITS PREPARATION AND ITS USE FOR THE PREPARATION OF ANTHRAQUINONES BASF Aktiengesellschaft (DE) 1982-03-31 EP disclosed
US-4255285-A FOR THE CATALYTIC OXIDATION OF A 1-PHENYLINDAN TO AN ANTHRAQUINONE; ATOMIZING AN AQUEOUS VANADIUM COMPOUND TO COAT AND ROAST MOVING CARRIER PARTICLES BASF AKTIENGESELLSCHAFT (DE) 1981-03-10 US disclosed
EP-0004591-A1 Shell catalyst, process for its preparation and its use for the preparation of anthraquinones BASF Aktiengesellschaft (DE) 1979-10-17 EP disclosed