Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135558 | 0.94 | ELANE (0.55) | ELANEKDM4ELMNAGPBAR1ALDH1A1 | |
| SCHEMBL10572626 | 0.88 | ELANE (0.52) | ELANEKDM4ELMNAGPBAR1ESR1 | |
| SCHEMBL11264066 | 0.88 | ELANE (0.43) | ELANEKDM4ELMNAALDH1A1TDP1 | |
| SCHEMBL11155898 | 0.86 | ELANE (0.51) | ELANEKDM4ELMNAGPBAR1ESR1 | |
| SCHEMBL10571626 | 0.85 | ELANE (0.55) | ELANEKDM4ELMNAGPBAR1ESR1 | |
| SCHEMBL10572555 | 0.85 | ELANE (0.54) | ELANEKDM4ELMNAGPBAR1ESR1 | |
| SCHEMBL10568991 | 0.82 | ELANE (0.55) | ELANEGPBAR1 | |
| SCHEMBL11040766 | 0.81 | ELANE (0.42) | ELANEALDH1A1L3MBTL1 | |
| SCHEMBL11277393 | 0.80 | ELANE (0.55) | ELANEGPBAR1 | |
| SCHEMBL11276416 | 0.80 | ELANE (0.55) | ELANEGPBAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017970-B1 | NOVEL BETA-LACTAM DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | SANRAKU-OCEAN CO., LTD. (JP) | 1982-07-07 | — | — | EP | disclosed |
| EP-0017970-A1 | Novel beta-lactam derivatives and process for production thereof | SANRAKU-OCEAN CO., LTD. (JP) | 1980-10-29 | — | — | EP | disclosed |