SCHEMBL11298747

SCHEMBL11298747

CNC(=O)C1(C)CCCC(C)(C)CC1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.36
FFAR3 O14843 1/20 0.36
CETP P11597 2/20 0.33
CYP3A4 P08684 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.32
CCR2 P41597 1/20 0.31
DRD2 P14416 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22592201 0.89 CETP (0.41) P2RX7FFAR3CETPCYP3A4SMN1; SMN2
SCHEMBL10224418 0.89
SCHEMBL23199626 0.84 CETP (0.42) P2RX7FFAR3CETPCYP3A4SMN1; SMN2
SCHEMBL8567866 0.84
SCHEMBL8002686 0.82 CETP (0.44) P2RX7FFAR3CETPCYP3A4SMN1; SMN2
Hydrochloric Acid SCHEMBL27934607 0.80 CETP (0.43) P2RX7FFAR3CETPCYP3A4SMN1; SMN2
SCHEMBL18736272 0.78 CETP (0.39) P2RX7FFAR3CETPSMN1; SMN2ALDH1A1
SCHEMBL11292104 0.76 FFAR3 (0.67) FFAR3SMN1; SMN2ALDH1A1
SCHEMBL18737843 0.75 CETP (0.40) P2RX7FFAR3CETPSMN1; SMN2ALDH1A1
SCHEMBL11298532 0.74 FFAR3 (0.39) FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4318900-A STIMULANTS WILKINSON SWORD LIMITED (GB) 1982-03-09 US disclosed
US-4248859-A USED IN EDIBLE AND TOPICAL PREPARATIONS WILKINSON SWORD LIMITED (GB) 1981-02-03 US disclosed