Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071970 | 0.87 | CYP2C19 (0.56) | CYP2C19SMN1; SMN2POLBTOP1CYP2D6 | |
| SCHEMBL10533515 | 0.85 | CYP2C19 (0.49) | CYP2C19SMN1; SMN2TBXAS1POLBCYP2D6 | |
| SCHEMBL1716759 | 0.85 | CYP2C19 (0.49) | CYP2C19SMN1; SMN2TBXAS1POLBCYP2D6 | |
| SCHEMBL10533521 | 0.85 | CYP2C19 (0.49) | CYP2C19SMN1; SMN2TBXAS1POLBCYP2D6 | |
| SCHEMBL1716761 | 0.85 | CYP2C19 (0.49) | CYP2C19SMN1; SMN2TBXAS1POLBCYP2D6 | |
| SCHEMBL11117064 | 0.85 | CYP2C19 (0.49) | CYP2C19SMN1; SMN2TBXAS1POLBCYP2D6 | |
| SCHEMBL667322 | 0.80 | CYP2C19 (0.62) | CYP2C19SMN1; SMN2POLBCYP2D6SRC | |
| SCHEMBL11546369 | 0.78 | CYP2C19 (0.55) | CYP2C19SMN1; SMN2TBXAS1POLBCYP2D6 | |
| SCHEMBL30371912 | 0.76 | CYP2C19 (0.61) | CYP2C19SMN1; SMN2TBXAS1POLBCYP2D6 | |
| SCHEMBL1363093 | 0.76 | CYP2C19 (0.68) | CYP2C19SMN1; SMN2TBXAS1POLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281019-A | 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents | AMERICAN CYANAMID COMPANY (US) | 1981-07-28 | — | — | US | disclosed |