Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299124 | 1.00 | TDP1 (0.46) | TDP1APPKDM4EDUSP3MEN1 | |
| SCHEMBL11233360 | 0.89 | TDP1 (0.44) | TDP1APPLMNAEGFRCA12 | |
| SCHEMBL11233355 | 0.89 | TDP1 (0.44) | TDP1APPLMNAEGFRCA12 | |
| SCHEMBL11232269 | 0.89 | TDP1 (0.47) | TDP1APPKDM4ELMNAEGFR | |
| SCHEMBL11232273 | 0.89 | TDP1 (0.47) | TDP1APPKDM4ELMNAEGFR | |
| SCHEMBL11229891 | 0.85 | CA12 (0.57) | TDP1APPEGFRCA12CA1 | |
| SCHEMBL11229892 | 0.85 | CA12 (0.57) | TDP1APPEGFRCA12CA1 | |
| SCHEMBL11239738 | 0.81 | EGFR (0.48) | TDP1APPMEN1KMT2ALMNA | |
| SCHEMBL11239735 | 0.81 | EGFR (0.48) | TDP1APPMEN1KMT2ALMNA | |
| SCHEMBL11245563 | 0.81 | EGFR (0.54) | APPLMNAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |