Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147830 | 0.94 | MAPT (0.48) | MAPTLMNASMN1; SMN2TLR7GAA | |
| SCHEMBL11070898 | 0.86 | TLR7 (0.42) | MAPTLMNATLR7POLBKDM4E | |
| SCHEMBL11244265 | 0.82 | MAPT (0.53) | MAPTLMNASMN1; SMN2POLBCYP4Z1 | |
| SCHEMBL11460602 | 0.82 | MAPT (0.55) | MAPTLMNASMN1; SMN2POLBCYP4Z1 | |
| SCHEMBL5458743 | 0.82 | MAPT (0.60) | MAPTLMNASMN1; SMN2TLR7POLB | |
| SCHEMBL5204322 | 0.80 | MAPT (0.59) | MAPTLMNASMN1; SMN2POLBCYP4Z1 | |
| SCHEMBL10788407 | 0.80 | MAPT (0.53) | MAPTLMNASMN1; SMN2TLR7POLB | |
| SCHEMBL11458904 | 0.79 | MAPT (0.52) | MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL11473930 | 0.79 | MAPT (0.63) | MAPTLMNASMN1; SMN2POLBCYP4Z1 | |
| SCHEMBL11160724 | 0.78 | MEN1 (0.58) | MAPTLMNASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281019-A | 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents | AMERICAN CYANAMID COMPANY (US) | 1981-07-28 | — | — | US | disclosed |