SCHEMBL11299252

SCHEMBL11299252

CC(C)C[C@H](N)C(=O)N(C(=O)OC(C)(C)C)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LARS1 Q9P2J5 2/20 0.39
ANPEP P15144 2/20 0.39
RNPEP Q9H4A4 1/20 0.39
DNPEP Q9ULA0 1/20 0.39
SLC7A5 Q01650 2/20 0.37
AAK1 Q2M2I8 2/20 0.36
LTA4H P09960 1/20 0.36
ELANE P08246 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GPR88 Q9GZN0 1/20 0.36
LAP3 P28838 1/20 0.35
KIF11 P52732 1/20 0.35
MAPT P10636 1/20 0.34
SCN9A Q15858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5961039 0.84 SLC7A5 (0.47) ANPEPRNPEPDNPEPSLC7A5LTA4H
SCHEMBL5961037 0.84 SLC7A5 (0.47) ANPEPRNPEPDNPEPSLC7A5LTA4H
SCHEMBL27509941 0.84 SLC7A5 (0.47) ANPEPRNPEPDNPEPSLC7A5LTA4H
SCHEMBL11473563 0.81 MCL1 (0.41) SLC7A5AAK1MAPT
SCHEMBL8736767 0.78 MEN1 (0.43) SMN1; SMN2
SCHEMBL10712025 0.78 ANPEP (0.41) LARS1ANPEPRNPEPDNPEPSLC7A5
SCHEMBL30912971 0.77 MEN1 (0.36) AAK1SMN1; SMN2
SCHEMBL15020426 0.77 SMN1; SMN2 (0.38) SMN1; SMN2MAPT
SCHEMBL4528517 0.77 SLC7A5 (0.43) SLC7A5LTA4H
SCHEMBL3489862 0.76 ANPEP (0.47) ANPEPRNPEPDNPEPSLC7A5LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0060422-A2 Method for improving intestinal absorption of cephalosporin derivatives Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-09-22 EP disclosed