Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.54 |
| ▸ | HTR1D | P28221 | 2/20 | 0.54 |
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11293534 | 0.90 | TAAR1 (0.58) | TAAR1HTR1DNISCHADRA2BADRA2C | |
| SCHEMBL11293013 | 0.85 | TAAR1 (0.69) | TAAR1HTR1DNISCHADRA2BADRA2C | |
| SCHEMBL11288885 | 0.83 | TAAR1 (0.71) | TAAR1HTR1DNISCHADRA2BADRA2C | |
| SCHEMBL11290819 | 0.80 | TAAR1 (0.71) | TAAR1HTR1DNISCHADRA2BADRA2C | |
| SCHEMBL29765276 | 0.78 | ESR1 (0.43) | TAAR1MAPK1LMNAMAPT | |
| SCHEMBL10142828 | 0.77 | NISCH (0.60) | TAAR1HTR1DNISCHADRA2BADRA2C | |
| SCHEMBL11132599 | 0.76 | NISCH (0.53) | TAAR1HTR1DNISCHADRA2BADRA2C | |
| SCHEMBL11131504 | 0.76 | NISCH (0.53) | TAAR1HTR1DNISCHADRA2BADRA2C | |
| SCHEMBL989780 | 0.76 | NISCH (0.53) | TAAR1HTR1DNISCHADRA2BADRA2C | |
| SCHEMBL11128132 | 0.76 | NISCH (0.53) | TAAR1HTR1DNISCHADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064820-A1 | Substituted imidazole and imidazoline derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1982-11-17 | — | — | EP | disclosed |