Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403179 | 1.00 | HCAR2 (0.58) | HCAR2HCAR3GPR84PTGS2KCNH2 | |
| SCHEMBL11400077 | 1.00 | HCAR2 (0.58) | HCAR2HCAR3GPR84PTGS2KCNH2 | |
| SCHEMBL11415052 | 1.00 | HCAR2 (0.58) | HCAR2HCAR3GPR84PTGS2KCNH2 | |
| SCHEMBL21401553 | 0.87 | HCAR2 (0.58) | HCAR2HCAR3GPR84KCNH2 | |
| SCHEMBL28317128 | 0.87 | HCAR2 (0.58) | HCAR2HCAR3GPR84KCNH2 | |
| SCHEMBL21297657 | 0.86 | HCAR2 (0.57) | HCAR2HCAR3GPR84KCNH2 | |
| Bromide SCHEMBL31310739 | 0.86 | HCAR2 (0.57) | HCAR2HCAR3GPR84KCNH2 | |
| SCHEMBL5960663 | 0.85 | HCAR2 (0.57) | HCAR2HCAR3GPR84KCNH2 | |
| SCHEMBL17493883 | 0.85 | HCAR2 (0.53) | HCAR2HCAR3KCNH2 | |
| SCHEMBL2765959 | 0.80 | HCAR2 (0.56) | HCAR2HCAR3GPR84KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56073068-A | — | — | None | — | — | JP | disclosed |
| JP-S5673068-A | PYRAZOLECARBINOL DERIVATIVE | MORISHITA SEIYAKU KK | 1981-06-17 | — | — | JP | disclosed |
| EP-0029363-A1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-05-27 | — | — | EP | disclosed |